CompuServe Thread

#Don't freeze your kids

3 messages in this thread
#167057From: Rick McQuayFeb 10, 1995 9:12 AM
I conducted an experiment in which Hamster embryos were frozen. All survived with detrimental effects. They developed with severe behavioral problems, acting almost rabid. Approximately one year from the date of birth, all were dead. The causes of death for each was not determined. One was found to have a tumor. Two instances of death were not natural and merely coincidental.
#167139From: Vladimir SvetlovFeb 10, 1995 10:13 PM
Did you run any karyological and/or DNA fingerprinting assessment of state of those unfortunate freeze-thaw embryos? There are numerous indications that apart from general cytoxicity freezing-thawing has direct impact on genome… Vlad
#167208From: Rick McQuayFeb 11, 1995 9:36 AM
>>Did you run any karyological and/or DNA fingerprinting assessment of state of those unfortunate freeze-thaw embryos? There are numerous indications that apart from general cytoxicity freezing-thawing has direct impact on genome…<< No, it was a somewhat primitive experiment. Perhaps someday, I'll repeat the experiment, when I have better conditions.